Cancer Keys: Myeloma and C.R.A.B

MGUS and Myeloma: What’s the link?

Latest articles: MGUS is a benign condition which does not usually require treatment. However, a small number of patients diagnosed with MGUS will go on to develop myeloma. Understanding MGUS Monoclonal gammopathy of undetermined significance (MGUS) is a benign...

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#hellomynameis – Tom, Senior Media Technologist

Latest articles: With communication at the heart of GatewayC and fundamental to improving patient care, this blog series focuses on introductions and reflections from the team behind the programme. In this post, we’re introducing Tom, Senior Media Technologist. Could...

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Welcome to Cancer Keys, a regular bite-sized learning column brought to you by GatewayC in collaboration with Cancer Research UK.

 

Myeloma and C.R.A.B

C.R.A.B is the acronym designed to simplify the most typical clinical manifestations of multiple myeloma. Clinicians should consider the following indicators in a potential myeloma diagnosis:

C: Calcium – hypercalcaemia

R: Renal – any form of renal dysfunction

A: Anaemia (of unknown cause)

B: Bone – unexplained and persistent bone pain (often back pain)

Helpful hint

NICE NG12 guidelines advise that a very urgent protein electrophoresis and Bence-Jones protein urine test (within 48 hours) for patients with hypercalcaemia or leukopenia and a presentation that is consistent with myeloma.

 

Cancer Keys are a collaboration between GatewayC and Cancer Research UK. Visit GatewayC’s Myeloma – Early Diagnosis course here.

 

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