Cancer Keys: PPIs masking red flag symptoms for stomach cancer

Latest from the Blog

Cancer Keys: Jaundice and Pancreatic Cancer

Cancer Keys: Jaundice and Pancreatic Cancer

Potential pitfall: Jaundice can be a classic symptom of pancreatic cancer; about half of patients have jaundice when they first go to their GP. Yet, pancreatic cancer is difficult to diagnose as symptoms can vary or may be late, vague and non-specific. Helpful hint:...

read more
World Lymphoma Awareness Day

World Lymphoma Awareness Day

Tuesday 15th September 2020 It’s World Lymphoma Awareness Day. Why not increase your knowledge and complete our free online Lymphoma – Early Diagnosis course supported by Lymphoma Action? Lymphoma has many non-site specific symptoms and patients can often visit...

read more

Related Posts

Cancer Keys: Jaundice and Pancreatic Cancer

Cancer Keys: Jaundice and Pancreatic Cancer

Potential pitfall: Jaundice can be a classic symptom of pancreatic cancer; about half of patients have jaundice when they first go to their GP. Yet, pancreatic cancer is difficult to diagnose as symptoms can vary or may be late, vague and non-specific. Helpful hint:...

read more
Cancer Keys: Faecal Calprotectin

Cancer Keys: Faecal Calprotectin

Potential pitfall: Faecal calprotectin testing is an incredibly sensitive investigation for detecting the presence of inflammation. It is raised in a wide variety of conditions including malignancy, inflammatory bowel disease and alcohol misuse. It is therefore not...

read more

Proton Pump Inhibitors (PPIs) are widely used to treat acid reflux and dyspepsia. NICE cautions that PPIs can mask or alter symptoms of stomach cancer, leading to later diagnoses.

Potential Pitfall

Patients on PPIs who have developed stomach cancer may increase their doses to manage further acid reflux and dyspepsia, further masking red flag symptoms. However, symptoms may become resistant or alter in character – perhaps manifesting as pain rather than burning, for instance.

Helpful hint

NICE NG12 guidelines advise to consider non‑urgent direct access upper gastrointestinal endoscopy to assess for stomach cancer in people aged 55 or over with treatment‑resistant dyspepsia.

Offer urgent direct access upper gastrointestinal endoscopy (to be performed within 2 weeks) to assess for stomach cancer in people with dysphagia, or aged 55 and over with weight loss and any of the following: upper abdominal pain, reflux, dyspepsia.

Cancer Keys are brought to you by GatewayC.

Download this Cancer Key here

Access GatewayC’s course on early diagnosis of stomach cancer here.

LinkedIn Twitter Facebook