Tuesday 5th January 2021 We are delighted to announce that the new Managing Physical Effects course is now available on GatewayC. According to Macmillan, at least 1 in 4 patients will experience consequences of their cancer or treatment that affect their quality of...
Cancer Keys: Leukaemia and Hepatosplenomegaly
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Swelling of the liver and spleen can be due to a number of causes such as infection, however in some cases it can be an indicator of leukaemia.
A patient with an enlarged spleen may present with a feeling of discomfort or pain behind the left ribs and feel full very quickly after eating.
Helpful hint
NICE NG12 guidelines advise that unexplained hepatosplenomegaly in children requires a referral for immediate specialist assessment, and in adults a very urgent full blood count (within 48 hours).
Be aware: an enlarged spleen can be a symptom of lymphoma. NICE NG12 guidelines advise to take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus or weight loss.
Cancer Keys are brought to you by GatewayC.
Download this Cancer Key here.
Access GatewayC’s course: Acute Leukaemia – Early Diagnosis here.

Latest from the Blog
NEW COURSE: Managing Physical Effects
Tuesday 5th January 2021 We are delighted to announce that the new Managing Physical Effects course is now available on GatewayC. According to Macmillan, at least 1 in 4 patients will experience consequences of their cancer or treatment that affect their quality of...
GatewayC’s top tips from 2020
Monday 4th January 2021 2020 certainly provided challenges and many new learning opportunities for primary care professionals across England. With this in mind, we have rounded up some of our most popular 2020 tips. Take a look below! COVID-19 and neutropenic sepsis...
Related Posts
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Potential pitfall: Fatigue is a common presenting problem in primary care, and yet it is important to remember that fatigue can represent a more serious condition. Many patients with chronic myeloid leukaemia (CML) have few or no symptoms at the time they are...
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Potential pitfall: Overlapping lung cancer and COVID-19 symptoms means that the message to patients about early diagnosis is negated by the messages necessary to control the COVID pandemic. Helpful hint: Consider the following action if a patient presents with...