Cancer Keys: Leukaemia and Hepatosplenomegaly

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Swelling of the liver and spleen can be due to a number of causes such as infection, however in some cases it can be an indicator of leukaemia.

A patient with an enlarged spleen may present with a feeling of discomfort or pain behind the left ribs and feel full very quickly after eating.

Helpful hint

NICE NG12 guidelines advise that unexplained hepatosplenomegaly in children requires a referral for immediate specialist assessment, and in adults a very urgent full blood count (within 48 hours).

Be aware: an enlarged spleen can be a symptom of lymphoma. NICE NG12 guidelines advise to take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus or weight loss.

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Latest from the Blog

Meet the specialists: diagnosing ovarian cancer Q&A

Meet the specialists: diagnosing ovarian cancer Q&A

15th January 2021 Missed our free GatewayC webinar on Diagnosing Ovarian Cancer? Watch our recording here. In this webinar, GatewayC met Professor Gordon Jayson, Professor of Medical Oncology at The Christie NHS Foundation Trust, who answered key questions from our...

read more

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