Monday 18th January 2021 GatewayC have produced a list of cancer charity support lines for people who may be worried about their cancer diagnosis, or are concerned about how COVID-19 might affect their cancer treatment. Please download this PDF resource or find the...
Cancer Keys: Leukaemia and Hepatosplenomegaly
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Swelling of the liver and spleen can be due to a number of causes such as infection, however in some cases it can be an indicator of leukaemia.
A patient with an enlarged spleen may present with a feeling of discomfort or pain behind the left ribs and feel full very quickly after eating.
Helpful hint
NICE NG12 guidelines advise that unexplained hepatosplenomegaly in children requires a referral for immediate specialist assessment, and in adults a very urgent full blood count (within 48 hours).
Be aware: an enlarged spleen can be a symptom of lymphoma. NICE NG12 guidelines advise to take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus or weight loss.
Cancer Keys are brought to you by GatewayC.
Download this Cancer Key here.
Access GatewayC’s course: Acute Leukaemia – Early Diagnosis here.

Latest from the Blog
Resource: charity support lines for people living with cancer
Monday 18th January 2021 GatewayC have produced a list of cancer charity support lines for people who may be worried about their cancer diagnosis, or are concerned about how COVID-19 might affect their cancer treatment. Please download this PDF resource or find the...
Meet the specialists: diagnosing ovarian cancer Q&A
15th January 2021 Missed our free GatewayC webinar on Diagnosing Ovarian Cancer? Watch our recording here. In this webinar, GatewayC met Professor Gordon Jayson, Professor of Medical Oncology at The Christie NHS Foundation Trust, who answered key questions from our...
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Potential pitfall: A migraine headache is typically a unilateral, frontal, throbbing headache which may be associated with photophobia or phonophobia. Although the intensity can vary, the characteristics of the headache tend not to change. Helpful hint: The most...
Cancer Keys: Thresholds for a Positive FIT Test in Symptomatic Patients
Potential pitfall: A negative bowel screening test should not be used to make decisions about referral in a symptomatic patient. Sensitivity levels have been set very differently for screening and symptomatic Faecal Immunochemical Tests (FIT). Helpful hint: The...