Cancer Keys: Leukaemia and Hepatosplenomegaly

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Swelling of the liver and spleen can be due to a number of causes such as infection, however in some cases it can be an indicator of leukaemia.

A patient with an enlarged spleen may present with a feeling of discomfort or pain behind the left ribs and feel full very quickly after eating.

Helpful hint

NICE NG12 guidelines advise that unexplained hepatosplenomegaly in children requires a referral for immediate specialist assessment, and in adults a very urgent full blood count (within 48 hours).

Be aware: an enlarged spleen can be a symptom of lymphoma. NICE NG12 guidelines advise to take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus or weight loss.

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Latest from the Blog

Meet the specialists: lung cancer vs COVID-19 Q&A

Meet the specialists: lung cancer vs COVID-19 Q&A

Friday 30th October 2020 Missed our free GatewayC webinar on Lung Cancer vs COVID-19? Watch our recording here. In this webinar GatewayC met Dr Matthew Evison, Consultant Chest Physician and Director of the Lung Pathway Board, and Dr Seamus Grundy, Consultant...

read more
Meet the specialists: acute leukaemia Q&A

Meet the specialists: acute leukaemia Q&A

Friday 23rd October 2020 Missed our free GatewayC webinar on Acute Leukaemia? Watch our recording here. In this webinar GatewayC met Dr Amit Patel, a Consultant in Cellular Therapies and Stem Cell Transplantation, who answered key questions from our audience. These...

read more

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Cancer Keys: False negative FIT results

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Whilst FIT can be a good indicator of bowel cancer, inflammatory bowel disease and sometimes precursors of cancer, some symptomatic patients can still have false negative results. With this in mind, how should you proceed? Potential Pitfall A normal result can miss...

read more