Cancer Keys: Thresholds for a Positive FIT Test in Symptomatic Patients

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Potential pitfall:

A negative bowel screening test should not be used to make decisions about referral in a symptomatic patient. Sensitivity levels have been set very differently for screening and symptomatic Faecal Immunochemical Tests (FIT).

Helpful hint:

The screening sensitivity threshold is 120ug/g in England (150ug/g in Wales and 80ug/g in Scotland). In symptomatic patients, the NICE DG30 guidance recommends that results should be reported using a threshold of 10 micrograms of haemoglobin per gram of faeces.

Cancer Keys are brought to you by GatewayC.

Download this Cancer Key here

Read the NICE NG12 guidance here

Access GatewayC’s Faecal Immunochemical Test (FIT) course here

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Latest from the Blog

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Potential pitfall: Jaundice can be a classic symptom of pancreatic cancer; about half of patients have jaundice when they first go to their GP. Yet, pancreatic cancer is difficult to diagnose as symptoms can vary or may be late, vague and non-specific. Helpful hint:...

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Potential pitfall: Faecal calprotectin testing is an incredibly sensitive investigation for detecting the presence of inflammation. It is raised in a wide variety of conditions including malignancy, inflammatory bowel disease and alcohol misuse. It is therefore not...

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