Potential pitfall: Irritable bowel syndrome (IBS) is a common disorder and can mimic the symptoms of ovarian cancer. Helpful hint: NICE NG12 guidelines recommend carrying out appropriate tests for ovarian cancer in any woman of 50 or over who has experienced symptoms...
Cancer Keys: Thresholds for a Positive FIT Test in Symptomatic Patients
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Potential pitfall:
A negative bowel screening test should not be used to make decisions about referral in a symptomatic patient. Sensitivity levels have been set very differently for screening and symptomatic Faecal Immunochemical Tests (FIT).
Helpful hint:
The screening sensitivity threshold is 120ug/g in England (150ug/g in Wales and 80ug/g in Scotland). In symptomatic patients, the NICE DG30 guidance recommends that results should be reported using a threshold of 10 micrograms of haemoglobin per gram of faeces.
Cancer Keys are brought to you by GatewayC.
Download this Cancer Key here
Read the NICE NG12 guidance here
Access GatewayC’s Faecal Immunochemical Test (FIT) course here

Latest from the Blog
Cancer Keys: Ovarian Cancer and New-Onset Irritable Bowel Syndrome
Potential pitfall: Irritable bowel syndrome (IBS) is a common disorder and can mimic the symptoms of ovarian cancer. Helpful hint: NICE NG12 guidelines recommend carrying out appropriate tests for ovarian cancer in any woman of 50 or over who has experienced symptoms...
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4th February 2021 The 4th of February 2021 marks World Cancer Day 2021. This year, the theme #IAmAndIWill encourages us to recognise our own commitments to improving cancer outcomes. GatewayC now has over 19 free online cancer education courses which can help primary...
Related Posts
Cancer Keys: COVID-19 and Neutropenic Sepsis
Neutropenic sepsis is a potentially fatal complication of anticancer treatment (particularly chemotherapy). Helpful hint: NICE have produced a COVID-19 rapid guideline on the delivery of systemic anticancer treatments. If patients present with COVID-19 symptoms this...
Cancer Keys: Pancreatic Cancer and New-Onset Diabetes
Potential pitfall: In the early course of the disease, pancreatic cancer may not cause any signs or symptoms. However, sudden onset diabetes in groups of patients for whom this would be unexpected can be an early indicator. Helpful hint: NICE NG12 guidelines recommend...