Cancer Keys: Chronic Myeloid Leukaemia and Fatigue

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Potential pitfall:

Fatigue is a common presenting problem in primary care, and yet it is important to remember that fatigue can represent a more serious condition. Many patients with chronic myeloid leukaemia (CML) have few or no symptoms at the time they are diagnosed. Therefore, CML can be an incidental finding following a blood test as part of a routine check-up for fatigue, malaise or another condition.

Helpful hint:

NICE NG12 guidelines recommend GPs to consider a very urgent full blood count (within 48 hours) to assess for leukaemia in adults with any of the following: pallor, persistent fatigue, unexplained fever, unexplained persistent or recurrent infection, generalised lymphadenopathy, unexplained bruising, unexplained bleeding, unexplained petechiae and hepatosplenomegaly.

Please note: if the disease has progressed symptoms become more likely.

Cancer Keys are brought to you by GatewayC.

Download this Cancer Key here

Read the NICE NG12 guidance here

Access GatewayC’s Chronic Leukaemia – Early Diagnosis course here

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Latest from the Blog

Cancer Keys: Migraines versus Brain Tumours

Cancer Keys: Migraines versus Brain Tumours

Potential pitfall: A migraine headache is typically a unilateral, frontal, throbbing headache which may be associated with photophobia or phonophobia. Although the intensity can vary, the characteristics of the headache tend not to change. Helpful hint: The most...

read more
Tips on what to include in your referral letter

Tips on what to include in your referral letter

Friday 21st August 2020 Did you miss our free webinar on Suspected Cancer Referrals and COVID-19? Watch it here. Miss Susannah Penney, Consultant Head, Neck and Thyroid Surgeon, receives over 2000 cancer referrals a year. When making a suspected cancer referral, are...

read more

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Cancer Keys: False negative chest X-rays

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False negative chest X-rays The main investigation for suspected lung cancer in primary care is a chest X-ray. However, reports show that some patients with normal chest X-rays still transpire to have lung cancer. Potential pitfall Although most large lung cancers can...

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Cancer Keys: Sudden onset diabetes

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Sudden onset diabetes Symptoms of pancreatic cancer can often be vague; however sudden onset diabetes can be a potential indicator of the disease. Potential pitfall Diabetes, especially Type 2, is common among the general population. However, consideration should be...

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