Monday 4th January 2021 2020 certainly provided challenges and many new learning opportunities for primary care professionals across England. With this in mind, we have rounded up some of our most popular 2020 tips. Take a look below! COVID-19 and neutropenic sepsis...
Cancer Keys: The two tests that will diagnose at least 90% of myeloma patients
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Myeloma investigations
If you are suspicious of myeloma following blood results, there are two pertinent investigations that can be ordered in primary care to give a strong case for referral:
1. Serum protein electrophoresis test
2. Bence-Jones protein urine test
Potential Pitfall
If you test for serum protein electrophoresis alone, you will identify only 2/3 of patients.
Helpful hint
Most patients with untreated myeloma have a monoclonal immunoglobulin peak in serum, urine, or both. A combination of serum protein electrophoresis and Bence-Jones protein urine test will diagnose up to 95% of patients with myeloma without any form of imaging. NICE NG12 guidelines suggest making a suspected cancer referral for patients whose investigation results indicate myeloma.
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