29th January 2021 Missed our free GatewayC LIVE webinar? Watch our recording here. In this webinar, GatewayC met Professor Robert Duncombe, Director of Pharmacy at The Christie NHS Foundation Trust and Dr Neil Bayman, Consultant Clinical Oncologist and Associate...
Cancer Keys: The two tests that will diagnose at least 90% of myeloma patients
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Myeloma investigations
If you are suspicious of myeloma following blood results, there are two pertinent investigations that can be ordered in primary care to give a strong case for referral:
1. Serum protein electrophoresis test
2. Bence-Jones protein urine test
Potential Pitfall
If you test for serum protein electrophoresis alone, you will identify only 2/3 of patients.
Helpful hint
Most patients with untreated myeloma have a monoclonal immunoglobulin peak in serum, urine, or both. A combination of serum protein electrophoresis and Bence-Jones protein urine test will diagnose up to 95% of patients with myeloma without any form of imaging. NICE NG12 guidelines suggest making a suspected cancer referral for patients whose investigation results indicate myeloma.
Cancer Keys are brought to you by GatewayC.
Download this Cancer Key here.
Access GatewayC’s Myeloma – Early Diagnosis course.

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